requiring supplemental oxygen – Communicable Diseases Research

Characteristics and treatment of hospitalized pregnant women with Coronavirus Disease 2019, COVID-19

Research article

Published on 2022-11-012022-10-05
Journal: American journal of obstetrics & gynecology MFM
[Category] 임상, 치료법,

Remdesivir for the treatment of COVID-19: a systematic review and meta-analysis

Review article

Published on 2022-09-012022-10-05
Journal: Clinical microbiology and infection : the official
[Category] COVID19(2023년), SARS, 임상, 치료법,

[키워드] 95% CI assessment Bayesian benefit clinically conducted coronavirus COVID-19 criteria eight eligibility criteria evaluate Hospitalized hospitalized patient Inpatient mechanical ventilation Meta-analysis Mortality Neutral objective oxygen Oxygen requirements participant Participants Patient patients with COVID-19 performed Placebo Primary outcome Probability random effect randomized trials recommendation reduce reduced Remdesivir requiring supplemental oxygen Result risk risk of bia risk reduction searched Standard of care stratified supplemental oxygen systematic review the patient therapy Treatment with COVID-19 World Health Organization
[DOI] 10.1016/j.cmi.2022.04.018 [Article Type] Review article

Mesenchymal stromal cell therapy for acute respiratory distress syndrome due to coronavirus disease 2019

2019년 코로나바이러스로 인한 급성호흡곤란증후군에 대한 중간엽 기질세포 치료

Article

Published on 2022-08-012022-09-12
Journal: Cytotherapy
[Category] 진단,

[키워드] 95% CI 95% confidence interval acute lung injury acute respiratory distress acute respiratory distress syndrome Allogeneic anti-inflammatory property ARDS C-reactive protein case sery cells clinical outcomes coronavirus disease COVID-19 COVID-19-associated ARDS declined discharged dose eligible follow-up period high mortality hospital Inflammatory cytokine intensive care Kidney injury less liver Lung disease mechanical ventilation mechanically ventilated median time Mesenchymal stromal cell mesenchymal stromal cells. moderate MSC MSCs nine Patient patients patients died remained Remestemcel-L requiring supplemental oxygen resulting Safe shown significantly stromal cell syndrome therapy treat treated were excluded
[DOI] 10.1016/j.jcyt.2022.03.006 PMC 바로가기 [Article Type] Article

Bone Marrow-Derived Mesenchymal Stromal Cell Therapy in Severe COVID-19: Preliminary Results of a Phase I/II Clinical Trial

Clinical Trial

Published on 2022-07-042022-10-04
Journal: Frontiers in Immunology
[Category] COVID19(2023년), SARS, 임상,

[키워드] acute respiratory distress acute respiratory distress syndrome adverse effect ARDS bone Bone marrow cells cellular cellular therapy clinical Cohort control patient control patients COVID-19 COVID-19 disease Critical D-dimer value Dexamethasone Efficacy Endocarditis evaluate extracorporeal membrane oxygenation group high mortality High-flow nasal oxygen Immune cell Immune-mediated induce Inflammation Inflammatory response intensive care intensive care unit (ICU) interval intravenous infusion invasive Invasive mechanical ventilation limit mechanical ventilation median mesenchymal stromal cells. MSC MSC-treated MSCs nasal no significant difference observation outcome oxygen Patient patients phase phenotype Randomized controlled trial Regulatory reported required requiring supplemental oxygen Result Safe SARS-CoV-2 severe COVID-19 significantly higher significantly lower Statistical tests stimulate stroke stromal cell survival syndrome therapy tissue repair treated Trial
[DOI] 10.3389/fimmu.2022.932360 PMC 바로가기 [Article Type] Clinical Trial

Remdesivir for the treatment of patients hospitalized with COVID-19 receiving supplemental oxygen: a targeted literature review and meta-analysis

산소 보충을 받고 있는 COVID-19로 입원한 환자의 치료를 위한 렘데시비르: 표적 문헌 검토 및 메타 분석

Review

Published on 2022-06-102022-09-11
Journal: Scientific Reports
[Category] 임상, 치료법,

A Cost-Effectiveness Analysis of Remdesivir for the Treatment of Hospitalized Patients With COVID-19 in England and Wales

Research article

Published on 2022-05-012022-10-05
Journal: Value in health : the journal of the International
[Category] 임상, 치료법,

Effect of Sotrovimab on Hospitalization or Death Among High-risk Patients With Mild to Moderate COVID-19: A Randomized Clinical Trial

Randomized Controlled Trial

Published on 2022-04-052022-10-05
Journal: JAMA
[Category] COVID19(2023년), SARS, 변종, 임상, 진단, 치료제,

[키워드] 1:1 24 hour absolute difference acute illness adjusted adjusted relative risk Adverse adverse event age all-cause hospitalization Brazil Canada clinical clinical trial collected conducted COVID-19 COVID-19 progression Critical death diarrhea Disease progression duration of follow-up Effect Efficacy end point evaluate event favor Follow-up high-risk patient Hospitalization increased risk infected with SARS-CoV-2 interim analysis intravenous intravenous dose Latinx management mechanical ventilation median age Mild Moderate COVID-19 neutralizing antibody outcome Patient patients randomized patients with COVID-19 Placebo Pneumonia Prevent Primary outcome progression proportion Randomized reduced requiring supplemental oxygen risk risk factor SARS-CoV-2 variant secondary outcome severe disease significantly Sotrovimab Spain statistically significant Support symptomatic tested the median those with comorbidity Treatment treatment group
[DOI] 10.1001/jama.2022.2832 PMC 바로가기 [Article Type] Randomized Controlled Trial

SARS-CoV-2 attacks the weakest point – COVID-19 course in a pediatric patient with Friedreich’s ataxia

Case report

Published on 2022-04-012022-10-05
Journal: International Journal of Infectious Diseases
[Category] COVID19(2023년), SARS, 변종, 치료제,

Steroid therapy and antiviral treatment in SARS-CoV-2 pneumonia: clinical contexts and indications

SARS-CoV-2 폐렴에서 스테로이드 요법 및 항바이러스 치료: 임상적 맥락 및 적응증

Review

Published on 2022-04-012022-09-11
Journal: Revista española de quimioterapia : publicación
[Category] COVID19(2023년), SARS, 치료제,

[키워드] 28-day mortality Antiviral treatment benefit Clinical improvement clinical trial complications Corticosteroids Critically ill Critically ill patient critically ill patients decrease Dexamethasone Disease progression drug Effectiveness Fluid management group Health Organization higher risk include indication measure mechanical ventilation Meta-analysis Mortality oxygen Oxygen therapy Patient patients with COVID-19 per day performed Placebo RECOVERY trial reduction in Remdesivir requiring supplemental oxygen routine care SARS-CoV-2 Standard of care steroid therapy subgroup analysis supplemental oxygen supportive care systemic corticosteroid systemic corticosteroids Trial WHO with COVID-19 World Health Organization
[DOI] 10.37201/req/s01.13.2022 PMC 바로가기 [Article Type] Review

Effect of Androgen Suppression on Clinical Outcomes in Hospitalized Men With COVID-19: The HITCH Randomized Clinical Trial

Randomized Controlled Trial

Published on 2022-04-012022-10-04
Journal: JAMA Network Open
[Category] COVID19(2023년), SARS, 임상,

[키워드] adverse event Affair age all-cause mortality analyzed androgen antiandrogen Antibiotics Asthma baseline cardiovascular disease Care Cell chronic obstructive chronic respiratory clinical Clinical improvement Clinical outcome common Comorbidity convalescent plasma COVID-19 COVID-19 severity Department determine Dexamethasone diabete disease severity disorder double-blind Effect Efficacy end point End points enrolled Hemodialysis hospital Hospitalization Hospitalized hypertension IMPROVE Inpatient interim analysis intravenous fluids Invasive mechanical ventilation mechanical ventilation median men Mortality no difference no significant difference outcome Patient patients patients randomized Peritoneal dialysis Placebo placebo group placebo-controlled primary end point protease randomization Randomized randomized clinical trial reduce expression Remdesivir requiring supplemental oxygen saline placebo SARS-CoV-2 entry secondary Serious Adverse Event severity of COVID-19 Standard standard care stratified subcutaneous dose supplemental oxygen suppression temperature the placebo group therapy TMPRSS2 Trial usual care vasopressor support veteran with COVID-19
[DOI] 10.1001/jamanetworkopen.2022.7852 PMC 바로가기 [Article Type] Randomized Controlled Trial